Studies of the importance of the human microbiome have demonstrated that microbial
metabolites of fermentation of our dietary products (e.g. dietary fiber) have a multitude of
health benefits. The investigators aim to determine whether supplementation of asthmatic
children with soluble corn fiber alongside standard of care reduces airway inflammation
driven by the gut microbial metabolites acetate, propionate, or butyrate (short chain fatty
acids).
Phase:
Phase 2
Details
Lead Sponsor:
Phoenix Children's Hospital
Collaborators:
Flinn Foundation Mayo Clinic Northern Arizona University