Overview

Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer

Status:
Terminated
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
This multi-institutional phase I/II clinical trial will test the tolerability and efficacy of the combination sorafenib and topotecan in patients with recurrent ovarian cancer, which is platinum-resistant (recurrence within 6 months from completing platinum based therapy) or refractory (progressive disease during platinum based therapy).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Daniela Matei, MD
Collaborators:
Bayer
Hoosier Cancer Research Network
Treatments:
Niacinamide
Sorafenib
Topotecan