Sorafenib and Vinorelbine in Treating Women With Stage IV Breast Cancer
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Drugs used in chemotherapy, such as vinorelbine, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving sorafenib together with vinorelbine may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of sorafenib when
given together with vinorelbine and to see how well they work in treating women with stage IV
breast cancer.