Overview

Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors

Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
The aim of this multicenter randomized phase II trial is to determine the efficacy of sorafenib and irinotecan combination versus irinotecan monotherapy or versus sorafenib monotherapy in metastatic colorectal cancer patients with KRAS mutated tumors after failure of all active drugs known to be effective.
Phase:
Phase 2
Details
Lead Sponsor:
Institut du Cancer de Montpellier - Val d'Aurelle
Treatments:
Camptothecin
Irinotecan
Niacinamide
Sorafenib