Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland
Status:
Completed
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
Pain after transurethral resection of prostate is considered mild to moderate severity from
detrusor muscle spasm and traction from urinary catheter. Numerous pain relieve methods have
been studied including spinal opioids, spinal anesthesia with local anesthetic and
dexmedetomidine, periprostatic nerve blockade with bupivacaine and mixing of prilocaine with
distilled water irrigation while undergoing a procedure. Most of patients having this
procedure are in elderly period, thus many anesthetists avoided spinal morphine which may
cause respiratory depressant effect postoperatively. Although previous studies showed
effectiveness of spinal morphine 25-200 mcg, some patients suffered from neuraxial opioid
side effects.
The aim of this study is to demonstrate efficacy of local anesthetic with intrathecal
morphine 50 mcg providing pain relieve after transurethral resection of prostate compare to
spinal anesthesia with sole local anesthetic.