Spinal Versus Epidural Analgesia in Laparotomic Liver Surgery

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of spinal analgesia for minor laparotomic hepatectomy compared with epidural analgesia, monitoring visual analog scale (VAS). The investigators expect at least the same post-operative pain control in the two groups (non inferiority of pain control with spinal analgesia compared to epidural analgesia). Second endpoint is to verify whether after spinal analgesia there is a decrease in patient's length of hospitalization according to enhanced recovery after surgery (ERAS) principles.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ospedale San Raffaele
• Treatments: Acetaminophen; Ketorolac; Ketorolac Tromethamine; Ropivacaine; Sufentanil

Criteria

Inclusion Criteria:

• Age > 18 years old

• Hospitalized patients

• Surgical indication for minor laparotomic anterior liver resection (II, III, IV and V hepatic segment resection)

• Surgical indication for laparotomic liver metastasectomy

• Ability to provide an informed consent

Exclusion Criteria:

• Patient refusal to provide informed consent

• Chronical therapy with opioids

• Pregnancy or breastfeeding

• Alcohol or drug abuse

• Planned or unplanned post-operative intensive care unit admission

• Contraindication to spinal/epidural analgesia

• Severe liver or renal failure

• Cognitive disorders, mental retard or psychiatric disorders

• Allergy to any drug used