Spironolactone Plus Metformin in Polycystic Ovary Syndrome

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators examined whether a combined therapy with low-dose spironolactone plus metformin is more effective than metformin alone in 52 overweight/obese Polycystic Ovary Syndrome (PCOS) patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Magna Graecia
• Treatments: Metformin; Spironolactone

Criteria

Inclusion Criteria:

• Overweight/obese patients with PCOS

Exclusion Criteria:

• Other causes of hyperandrogenism and

• Use of drugs including:

• oral contraceptive

• anti-hypertensive agents

• anti-diabetic drugs

• agents for weight loss