Overview Spironolactone for the Treatment of Melasma Status: Withdrawn Trial end date: 2021-01-01 Target enrollment: Participant gender: Summary The purpose of this study is to prospectively gather data on the efficacy and tolerability of spironolactone to treat refractory melasma and to compare treatment response of randomized 50 mg, 100mg, and 200mg per day dosing. Phase: Phase 1 Details Lead Sponsor: Medical University of South CarolinaTreatments: Spironolactone