The primary aim of this study is to conduct a 60-patient feasibility, acceptability, and
preliminary efficacy study of mSMART (Mobile App based Personalized Solutions and Tools for
Medication Adherence of Rx Pill), a smartphone application ("app") for improving medication
adherence among substance users. The investigators will compare 2 groups of cigarette smokers
undergoing a quit attempt with varenicline (Chantix): a) an experimental group using the
mSMART app on their smartphone and a MEMS Cap (Medication Event Monitoring System, a smart
pillbox that will a record a date and time-stamped medication event whenever pill box is
opened and closed, and thus allow for primary measurement of medication adherence) and b) a
control group using the MEMS Cap and mobile web-based surveys on their smartphone.
Phase:
Phase 1
Details
Lead Sponsor:
Duke University
Collaborators:
Intelligent Automation, Inc. National Institute on Drug Abuse (NIDA)