Standard vs High Dose of Unfractionated Heparin in the Incidence of Radial Artery Occlusion (DEFINITION) Trial.

• Status: Recruiting
• Trial end date: 2022-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Double blind single center clinical trial to compare the incidence of radial artery occlusion (RAO) using standard doses of Unfractionated Heparin (UFH) vs. high doses of UFH.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Nacional de Cardiologia Ignacio Chavez
• Treatments: Calcium heparin; Heparin

Criteria

Inclusion Criteria:

• Patients over 18 years of age, both genders.

• Successful transradial acess for an elective diagnostic coronary angiography.

Exclusion Criteria:

• Weight <50 Kg

• Puncture of the ipsilateral radial artery in the last month.

• Still ongoing effect of pre-procedural recently used oral anticoagulants.

• Use of enoxaparin in the past in the last 12 hours prior to the procedure.

• Use of unfractionated heparin in the last 6 hours prior the procedure

• Alterations in coagulation or platelets prone to bleeding or thrombotic complications.

• Anatomical alterations at the radial access site or radial artery.

• Arteriovenous fistula in the ipsilateral arm.

• History of major bleeding associated with the use of UFH.