Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
Status:
Not yet recruiting
Trial end date:
2023-12-15
Target enrollment:
Participant gender:
Summary
This is an open-label pilot trial to assess the safety and feasibility of a novel 6-week
psilocybin-assisted psychotherapy intervention to facilitate successful
tapering/discontinuation of opioid pain medication in adult patients receiving long-term
opioid therapy for chronic pain. Participation will last approximately 8 months and includes
two 25mg psilocybin-assisted psychotherapy sessions. The study will evaluate the incidence
and severity of adverse events during and after treatment, the number of participants who
drop out of the study for intervention-related reasons, and the self-reported benefits and
harms of the intervention.