Staphylococcus Aureus Decolonization Study

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather than the patient alone, and whether these methods are effective in preventing future Staph infections. The investigators hypothesize that there will be a greater number of households who are successful in eradicating the staph germ from the index patient when all members of the household participate than households where only the index patient is treated.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Mupirocin

Criteria

Inclusion Criteria:

Screening:

• Children aged 6 months to 21 years presenting with an active skin or soft tissue infection.

Enrollment:

• Positive MRSA culture from the abscess and from either the axilla, anterior nares or groin area (signifying both infection and colonization with MRSA).

Exclusion Criteria:

• Infants less than 6 months of age

• Dialysis or residence in a long term care facility over the past year

• Use of chlorhexidine or mupirocin in the past one month

• Pregnancy

• Immunodeficiency

• History of an adverse reaction to chlorhexidine or mupirocin.