Start or STop Anticoagulants Randomised Trial (SoSTART)
Status:
Completed
Trial end date:
2021-03-26
Target enrollment:
Participant gender:
Summary
Primary research question: For adults surviving spontaneous (non-traumatic) symptomatic
intracranial haemorrhage with persistent/paroxysmal atrial fibrillation/flutter (AF), does
starting full treatment dose oral anticoagulation (OAC) result in a beneficial net reduction
of all serious vascular events compared with not starting OAC?
Trial design: Investigator-led, multicentre, randomised, open, assessor-masked, parallel
group, clinical trial of investigational medicinal product (CTIMP) prescribing strategies.
Investigators plan for a pilot phase, followed by a safety phase.