Statin and Post-interventional Coronary Microcirculation Dysfunction

• Status: Unknown status
• Trial end date: 2014-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effect of statin on the coronary microcirculation dysfunction measured after percutaneous coronary intervention.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Samsung Medical Center
• Treatments: Atorvastatin; Atorvastatin Calcium

Criteria

Inclusion Criteria:

• A. Finished informed consent

• B. Stable angina with clinical indication of coronary angiography

• C. Age ≥ 21 year and ≤ 80 year

Exclusion Criteria:

• A.Without informed consent

• B.PCI target lesion is not adequate or not indicated for FFR/IMR study

• C.Prior myocardial infarction or interventional procedure for PCI target vessel

• D.Myocardial infarction within 30 days

• E.Usage of statin, current or within 1 month

• F.Prior bypass surgery

• G.Impaired renal function (Creatinine > 2.0 mg/dL)

• H.Impaired left ventricular function (ejection fraction < 40%)

• I.Active hepatitis or abnormal hepatic transaminase level (> 3 ULN)

• J.Contraindication for long-term antiplatelet agent or statin

• K.Planning or potential of pregnancy

• L.Neoplastic disease without evidence of treatment completion

• M.Impaired general condition