Statin for Immunomudulation in Sepsis

• Status: Unknown status
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether atorvastatin can improve the inflammatory answer in the septic patients

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital de Clinicas de Porto Alegre
• Treatments: Atorvastatin

Criteria

Inclusion Criteria:

• clinical diagnosis of several sepsis or shock septic

• no more than twenty four hours than diagnosis

Exclusion Criteria:

• use of statins in the last thirty days

• unequivocal indication for statin treatment

• active treatment with imunosuppressors drugs

• High risk of rhabdomyolysis: multiple trauma, crush injuries, baseline creatinine kinase > three times upper limit of normal

• diagnosis of AIDS

• unable to receive enteral medications

• pregnancy

• expected survival of less than 48 hours