Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy

• Status: Recruiting
• Trial end date: 2026-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The STAREE-Mind imaging sub-study will examine the effect of statin treatment over a 4-year period, compared with placebo, on markers of brain health.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Monash University
• Collaborator: National Health and Medical Research Council, Australia
• Treatments: Atorvastatin

Criteria

Inclusion Criteria:

• Participants in the STAREE RCT and eligible for randomisation to study medication.

• Men and women

• Aged ≥70 years

• Living independently in the community

• Willing and able to provide informed consent and agree to participate in brain neuroimaging.

• Able to attend one of the 2 sites (in Melbourne and Brisbane) where the imaging will take place.

Exclusion Criteria:

• Contraindications to have magnetic resonance neuroimaging performed.

• History of invasive brain surgery or known structural bran abnormalities.