Statins to Reduce D-dimer Levels in Patients With Venous Thrombosis
Status:
Terminated
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
Elevated levels of D-dimer, a marker of procoagulant state, have been identified as a marker
of an increased risk of recurrent VTE. Statins have proven antithrombotic properties, as
suggested by the reduction of several prothrombotic markers, including D-dimer, in patients
at high risk of arterial thrombosis. Such antithrombotic properties could also be observed in
patients at high risk of venous thrombosis. Aim of the study is to assess the effect of
statins on D-dimer levels in patients with previous VTE after oral anticoagulant treatment
withdrawal.
Phase:
Phase 2
Details
Lead Sponsor:
Università degli Studi dell'Insubria
Treatments:
Atorvastatin Atorvastatin Calcium Fibrin fragment D