Stellate Ganglion Block: A Breakthrough Treatment for Post-Stroke Pharyngeal Dysphagia

• Status: Terminated
• Trial end date: 2023-05-17
• Target enrollment: 0
• Participant gender: All

Summary

This was a multicenter randomized controlled study. 66 post-stroke patients with pharyngeal dysphagia were randomly allocated to the observation group (n=33) or the control group (n=33). Both groups were provided with comprehensive rehabilitation including routine rehabilitation and swallowing function training. Besides, the observation group additionally underwent the stellate ganglion block (SGB). At admission and after 20-day treatment, Kubota water swallowing test, video fluoroscopic swallowing study (VFSS), and Rosenbek penetration-aspiration scale (PAS) were used to assess swallowing function.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zeng Changhao

Criteria

Inclusion Criteria:

• Age between 30 and 80 years;

• New-onset stroke, confirmed by head CT or MRI;

• The course of disease between 1 to 6 months;

• With pharyngeal dysphagia shown by VFSS;

• Stable vital signs;

• Voluntary participation in the study.

Exclusion Criteria:

• Allergy to Lidocaine injection or vitamin B12 injection;

• Severe cognitive impairment;

• Coagulation disorders;

• Severe dysfunction of organs including heart, lungs, kidney, liver, etc.;

• Complicated with other neurological diseases;

• With severe oral dysphagia (results of the VFSS oral phase as 2 or 3 points);

• Dysphagia caused by other diseases or reasons.