Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
Status:
RECRUITING
Trial end date:
2029-06-20
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients. It will also assess the safety of injecting morphine around the stellate ganglion via ultrasound guidance. The main questions it aims to answer are:
1\. Does morphine regulate stellate ganglion function to reduce myocardial I/R injury in AMI patients and improve one year outcome in AMI patients? 3. What medical problems do participants experience when receiving injected morphine around the stellate ganglion? Researchers will compare morphine to a placebo saline (as a control group) to determine whether stellate ganglion infiltration with morphine effectively treats patients with AMI following primary PCI.
Participants will:
* Receive a single injection of morphine or saline around the stellate ganglion.
* Evaluate the myocardial injury during their duration of hospital stay.
* Record their symptoms and any major adverse cardiovascular and cerebrovascular events within one year post-surgery.