Overview

Stem Cells Therapy in Advanced Heart Failure

Status:
Recruiting

Trial end date:
2022-07-01

Target enrollment:
0

Participant gender:
All

Summary

stem cells therapy may be a choice therapy for advanced heart failure patients refractory to medical therapy, internal cardiovertor with a defibrillator (ICD) recipients, and a previous history of myocardial infarction and coronary artery revascularization. These patients, without indication to receive a cardiac resynchronization therapy (CRT), may have a worsening of heart failure, and symptoms of coronary artery disease. In this study we have evaluated in consecutive 30 selected patients the amelioration in failing heart NYHA class, hospitalization rate, echocardiographic left ventricle functionality, and associated to reduction of angina after a treatment with stem cells intra thoracic infusion.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Second University of Naples
University of Campania "Luigi Vanvitelli"

Criteria

Inclusion Criteria:

- heart failure post coronary artery disease, refractory to maximal medical therapy,
previous coronary artery surgical revascularization.

Exclusion Criteria:

- inflammatory chronic diseases, neoplastic diseases.