Steroid Impregnated Tape in the Treatment of Over-granulating Peritoneal Dialysis Exit Sites
Status:
Completed
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
Kidney failure is a devastating illness requiring treatment with dialysis or transplantation
to preserve life. Individuals unable to have transplants are managed by peritoneal dialysis
(PD)or haemodialysis (HD). PD involves the placement of a soft, flexible plastic tube
(catheter) into the abdomen, allowing dialysis fluid to be drained in and out of the
peritoneal cavity. This catheter exits from a hole in the abdomen and occasionally patients
can have complications at this exit site. One possible complication is over-granulation.
Over-granulation occurs as the wound attempts to heal and the skin around the exit site
becomes red,'wet','bumpy' and stands 'proud' of the surrounding skin. An over-granulating
exit site can lead to discomfort, pain, bleeding and harbour infection. More serious
complications include dialysis failure, sepsis and death. There are several ways to treat
over-granulation but there is limited research evidence to demonstrate which treatment is
best. The study aims to compare current standard treatment which involves the application of
silver nitrate by qualified nursing staff to chemically burn the tissue away, with an
alternative treatment which involves the application of steroid impregnated tape to the area
of over-granulating tissue by the patient themselves.
Phase:
Phase 3
Details
Lead Sponsor:
University Hospital Birmingham NHS Foundation Trust