Steroid Sensitive Nephrotic Syndrome in Children

• Status: Active, not recruiting
• Trial end date: 2021-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Idiopathic nephrotic syndrome (INS) is one of the most common glomerular pathologies in children and corticosteroid therapy is its most effective treatment. The total duration of treatment ranges anywhere from two to six months, generally about 3 months. The main objective of our study is to test the feasibility of a shorter total duration (two months) of corticosteroid therapy in patients who show a quicker treatment response to the initial treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wayne State University
• Collaborators: Children's Hospital of Fudan University; Lady Hardinge Medical College; Mansoura University Children Hospital; Sawai Mansingh Medical College; Sidra Medical and Research Center

Criteria

Inclusion Criteria:

• Age 1 to <19 years

• Newly diagnosed INS

• Patient in remission with steroids

• Written informed consent/Assent for the study OR as required by the local IRB

Exclusion Criteria:

• Age < 1 year or ≥ 19 years

• Uncertainty about patient/parent adherence.

• Abnormal serum creatinine for patient age

• Steroid resistant nephrotic syndrome

• Any co-morbid condition that might require modification in treatment with steroids.