Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
Approximately 20,000 children per year in North America present to the hospital with severe
shock. Children who develop this condition have very low blood pressures and as a result may
suffer damage to their internal organs and may even die. Some children with this condition
may significantly benefit from the use of steroids but steroids in such patients may also
have potential side effects. Therefore it is important to study the use of steroids carefully
in these children. The STRIPES research program will examine the effectiveness and safety of
steroids in children. Before conducting a large, randomized controlled trial (RCT), a pilot
study (STRIPES Pilot Study) will be conducted in multiple sites across Canada. The STRIPES
Pilot Study will allow testing of the STRIPES study protocol in a smaller group of patients.
Phase:
Phase 4
Details
Lead Sponsor:
Children's Hospital of Eastern Ontario
Collaborators:
Alberta Children's Hospital British Columbia Children's Hospital IWK Health Centre London Health Sciences Centre Montreal Children's Hospital of the MUHC St. Justine's Hospital