Steroid Withdrawal in Pediatric Kidney Transplant Recipients
Status:
Terminated
Trial end date:
2005-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to examine the effects of withdrawing steroids on graft
rejection and kidney functions in kidney transplant recipients between the ages of 0 and 20
years (prior to their 21st birthday).
Graft survival has improved in recent years in children with kidney transplants. One bad side
effect of steroid maintenance therapy has been growth retardation. Doctors believe steroids
might be safely withdrawn in patients that are receiving other maintenance therapies. If
steroids are removed, children might catch up in their growth and also might have fewer side
effects of other kinds. This study evaluates whether steroid therapy can be withdrawn in a
way that does not increase graft rejection.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Cooperative Clinical Trials in Pediatric Transplantation