Steroids Helping Albuterol Responders Exclusively

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether corticosteroids are beneficial to children with bronchiolitis whose breathing gets better after being given a breathing treatment with albuterol.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospitals Cleveland Medical Center
• Treatments: Albuterol; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• diagnosis of bronchiolitis

• Respiratory Distress Assessment Index score of 4 or more

Exclusion Criteria:

• prior prescription of bronchodilators or inhaled corticosteroids

• birth at <36 weeks gestation

• chronic cardiac disease

• chronic pulmonary disease (including asthma)

• immunodeficiency

• non-topical steroid use in the prior week

• parents that don't understand English

• baseline systolic blood pressure >118 mmHg

• home oxygen use

• evidence of systemic fungal or varicella infection

• bronchodilator use in the prior week

• allergy to albuterol or corticosteroids