Steroids Versus ECP and Steroids as First-line Treatment of Grade II Acute GVHD
Status:
Not yet recruiting
Trial end date:
2026-01-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare as a first line of grade II skin acute GVHD
sconventional treatment with steroids alone to a combination of steroids and extracoporeal
photopheresis (ECP)
The primary end point will compare Freedom from treatment failure at 6 months from
randomization as defined by meeting all the following 4 conditions:
- to be alive
- without relapse of the hematological disease
- without having required a new line of treatment for acute GVHD
- without initiating a systemic treatment for chronic GVHD.