Steroids for Early Treatment of Radiation Retinopathy
Status:
Withdrawn
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
Radiation retinopathy is a known complication of ocular radiation therapy. To date there is
no known effective treatment. In addition to their anti-vascular endothelial growth factor
(VEGF) properties, corticosteroids decrease the retinal capillary permeability by increasing
the activity/density of tight junctions and acute inflammatory effects of radiation in
various tissues.