Stopping Benzodiazepines and Related Molecules Among Elderly Living in Residential Institutions

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Intervention randomized controlled open study with 2 parallel arms . The objective of this study is to evaluate the feasibility of stopping the benzodiazepines treatment in elderly living in nursing homes.

It will check that the judgment of these molecules has no pejorative effect on sleep or behavior of residents and does not induce withdrawal syndrome. Two patient groups will be constituted. One will begin a gradual withdrawal of benzodiazepines in six weeks. The other group will continue his treatment and withdrawal will be proposed after 8 weeks by his general practitioner (delayed intervention).

Effects on sleep will be assessed by wrist actimetry for 10 weeks and a sleep diary . The repercussions of withdrawal on behavior will be rated by the NPI scale.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Criteria

Inclusion Criteria:

• Residents aged 70 or older and institutionalized for over a month

• Receiving one or more benzodiazepines and related drugs for over 30 days;

• Corresponding to stop aspects of benzodiazepines and related drugs as recent best practice guidelines by the French health authority (HAS)

• Signature of informed consent by the patient attended or not his guardian, the guardian or a relative;

• General practitioner agreeing to adhere to recommendations.

Exclusion Criteria:

• psychiatric pathology,

• epilepsy

• end of life situation

• Refusal to participate (or representative if he is unable to consent).