Stress During Deep Sedation With Propofol With and Without Alfentanil

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized clinical trial of deep procedural sedation with propofol with and without supplemental alfentanil. Patients will be assessed for total and fractionated serum catecholamines before and after the procedure in addition to usual procedural sedation outcomes parameters to assess the adrenergic effect of propofol sedation without supplemental opioid.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hennepin Healthcare Research Institute; Minneapolis Medical Research Foundation
• Treatments: Alfentanil; Propofol

Criteria

Inclusion Criteria:

• patients who will require deep procedural sedation with propofol in the ED

Exclusion Criteria:

• age <18

• intoxication

• unable to provide informed consent

• allergy to propofol or alfentanil

• pregnant

• ASA physical status score > 2