Overview

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

Status:
RECRUITING
Trial end date:
2026-05-01
Target enrollment:
Participant gender:
Summary
The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM). Our goal is to compare a strict and permissive threshold. The strict threshold is defined as two abnormal values or more over a one-week period (two fasting values elevated, two of the same post prandial values elevated, or 1 fasting and 1 post prandial value elevated), whereas the permissive threshold is defined as 50% of values elevated over 1 week (50% of overall fasting values, 50% of postprandial values, or 50% of overall values).
Phase:
NA
Details
Lead Sponsor:
Thomas Jefferson University
Collaborator:
University of Rochester
Treatments:
Insulin
Insulin Detemir
Insulin Glargine
Insulin Lispro