Stroke Prevention With Abciximab in Carotid Endarterectomy
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
In the first portion of the study, the goal will be to determine the safety of the drug
Abciximab for use during and in the period after open carotid artery surgery. In addition,
using specialized ultrasound equipment (a probe that is placed on the outside of your skin of
your head), we will aim to measure the number of particles released around the time of
surgery while being treated with Abciximab. The second phase of the study will be determine
if Abciximab can safely reduce the number of particles released into the bloodstream around
the time of surgery in order to reduce the risk of stroke.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Rochester
Collaborator:
Eli Lilly and Company
Treatments:
Abciximab Antibodies, Monoclonal Immunoglobulin Fab Fragments