Structured Non-operative Treatment of Knee Osteoarthritis
Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test whether an algorithm for systematic non-surgical
treatment consisting of corrective insoles, neuromuscular training, weight loss, patient
education and pharmacological treatment with paracetamol, non steroidal anti inflammatory
drugs (NSAIDs) and Pantoprazole provides further improvement in pain, function and quality of
life than standard non-surgical treatment (information on the disease and how to treat it) in
patients with knee osteoarthritis.
The H1-hypothesis is that the treatment algorithm results in a greater increase in quality of
life and functional capacity and greater reduction in pain than standard treatment at the
primary endpoint, which is follow-up 12months after the start of the treatment.
See statistical analysis plan available under "Links" for further description of the study.
Phase:
N/A
Details
Lead Sponsor:
Northern Orthopaedic Division, Denmark
Collaborators:
Association of Danish Physiotherapists The Danish Rheumatism Association