Study Comparing Patients Taking Olanzapine and Patients Taking Aripiprazole on Learning of Vocational Skills
Status:
Completed
Trial end date:
2007-06-01
Target enrollment:
Participant gender:
Summary
STUDY PURPOSE: To study whether patients who have schizophrenia or schizoaffective disorder
and are randomly assigned to switch to aripiprazole prior to participation in a brief
vocational skills training (VST) will have improved cognitive functioning and learn more in
VST than those randomly assigned to stay on olanzapine. There is evidence that VST is
important in improving role functioning for schizophrenia patients, however, cognitive
impairments limit the ability of some patients to benefit from skills training approaches.
Patients switched from olanzapine to aripiprazole improve in terms of verbal learning and
verbal learning has been shown to be a strong predictor of community outcome. It is unclear
whether the cognitive benefits of switching to aripiprazole extend to improve learning of
vocational skills.
Phase:
N/A
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio