Overview

Study Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal Women

Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
0
Participant gender:
Female
Summary
This study will assess if itraconazole will affect the blood levels of Duavee when they are given together. This study will also assess if a subject's body size affects the blood levels of Duavee.
Phase:
Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Pfizer
Treatments:
Bazedoxifene
Estrogens
Estrogens, Conjugated (USP)
Hydroxyitraconazole
Itraconazole
Criteria
Inclusion Criteria:

- Generally healthy postmenopausal women, aged 40-64. Intact Uterus

Exclusion Criteria:

- The use of oral, vaginal, or transdermal estrogen, androgen or progestin-containing
medications within 30 days before study drug administration.