Study Evaluating The Coadministration of Begacestat And Donepezil

• Status: Completed
• Trial end date: 2009-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study examines the cardiac effects (effects on the heart) of administering donepezil and begacestat together to healthy subjects.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
• Collaborator: Pfizer
• Treatments: Donepezil

Criteria

Inclusion Criteria:

• Healthy

• Men and women of non-childbearing potential

• Non smoker or smoker of <10 cigarettes per day and able to refrain from smoking during study

• 18-50 years old

Exclusion Criteria:

• Any significant cardiovascular, hepatic, renal, respiratory, gastrointestinal, endocrine, immunologic, dermatologic, hematologic, neurologic, or psychiatric disease.

• Cardiac rhythm abnormalities

• Family history of cardiac risk factors