Overview

Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway

Status:
Completed
Trial end date:
2007-03-01
Target enrollment:
Participant gender:
Summary
To evaluate the effects of multiple oral doses of desvenlafaxine sustained release (DVS SR) and paroxetine on the biotransformation of codeine to morphine in healthy subjects. To assess the safety and tolerability of DVS SR and paroxetine when coadministered with codeine to healthy subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Wyeth is now a wholly owned subsidiary of Pfizer
Treatments:
Codeine
Desvenlafaxine Succinate
Paroxetine