Study: Treatment of Relapsed Lymphoid Malignancies With an Anti-Angiogenic Approach
Status:
Terminated
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
1.1 To determine the efficacy of a combination treatment of VP-16, chlorambucil,
dexamethasone, and vincristine in patients with relapsed/refractory hematological
malignancies.
1.2 To determine the toxicity profile of the above regimen in this patient population.
1.3 Evaluate the effect of low dose administration of chemotherapy on angiogenesis, and
correlate this with tumor responses.