Study With Healthy Japanese and Non-Asian Participants With BMS-986231

• Status: Completed
• Trial end date: 2017-05-26
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this Phase 1 study is to evaluate the safety, tolerability, PK, and pharmacodynamics (PD) of BMS-986231 in healthy Japanese and Non-Asian participants. There is no formal hypothesis to be statistically tested.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bristol-Myers Squibb

Criteria

Inclusion Criteria:

• Ancestry

• First generation Japanese

• Non-Asian with grandparents and parents of non-Asian descent

• Body weight greater than or equal to 45kg and less than or equal to 110kg

• Women of childbearing potential have specific birthcontrol methods

• Males sexually active with women of childbearing potential have specific birthcontrol methods

Exclusion Criteria:

• History of chronic illness

• Chronic headaches

• Recurrent dizziness

• Personal or family history of heart disease

• Personal history of bleeding diathesis