Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.

• Status: Not yet recruiting
• Trial end date: 2027-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation mechanism of acupuncture intervention on hot flashes based on integrated PET/MRI technology.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nanjing University of Traditional Chinese Medicine
• Collaborators: Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine; Hanzhong Hospital of Traditional Chinese Medicine; School of Life Science and Technology, Xi'an Jiaotong University; Xiang'an Hospital of Xiamen University
• Treatments: Gabapentin

Criteria

Inclusion Criteria:

• Diagnosis history of early breast cancer (stages Ⅰ to Ⅲ)

• TAged 30-75 years old;

• Has been on adjuvant hormone therapy (such as tamoxifen and/or aromatase inhibitors) with or without ovarian suppression for at least 4 weeks and is still in the course of treatment; (Reference: Premenstrual patients willing to take non-hormonal contraceptives);

• Patients who had hot flashes in the past month and had hot flashes more than 14 times per week (2 times per day) in the week before inclusion in the study

• Patients after surgery and chemotherapy (if any);

• Sign the informed consent and participate in the clinical observation voluntarily.

Exclusion Criteria:

• Breast cancer metastasis, is receiving breast cancer treatment;

• Those who started or changed hormone adjuvant therapy within a week, or planned to start therapy or changed hormone adjuvant therapy within 14 weeks;

• During pregnancy and lactation, bleeding or clotting disorder, or history of gabapentin allergy;

• Patients with kidney failure who have used anticonvulsants in the past year 11MRI claustrophobia.