Study of Antioxidants on Prostate Tumors in Men Undergoing Radical Prostatectomy for Prostate Cancer

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to see if an intervention of antioxidants(vitamin E, selenium and lycopene) can change (reduce) prostate tumor size and alter certain markers that can affect tumor growth and prostate cancer aggressiveness.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Health Network, Toronto
• Treatments: alpha-Tocopherol; Antioxidants; Carotenoids; Cholecalciferol; Ergocalciferols; Lycopene; Selenium; Tocopherols; Tocotrienols; Vitamin D; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

• Diagnosis of a Gleason score > or = to 7 adenocarcinoma of the prostate

• At least 30% of one core involved

• Radical prostatectomy planned

• Willingness to discontinue use of supplements at least 4 weeks prior to study intervention (for subjects using vitamin E, selenium or lycopene at time of consent)

• ability and willingness to consume study intervention for 6 - 8 weeks prior to radical prostatectomy.

Exclusion Criteria:

• Previous treatment for prostate cancer

• Current use of finasteride or dutasteride