Overview

Study of Bavituximab and Sorafenib In Patients With Advanced Liver Cancer

Status:
Completed
Trial end date:
2018-04-01
Target enrollment:
Participant gender:
Summary
This is a non-randomized, open-label, single-institution phase I/II therapeutic trial of bavituximab and sorafenib in patients with advanced hepatocellular carcinoma (HCC). This study will be activated at the UT Southwestern Medical Center, comprised of The Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Hospitals-St. Paul and Parkland Memorial Hospital System. Advanced HCC is defined as disease that is not amenable to surgical resection or orthotopic liver transplantation or is metastatic in nature.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Treatments:
Antibodies, Monoclonal
Bavituximab
Niacinamide
Sorafenib