Overview

Study of Bevacizumab in Combination With 5-FU, Oxaliplatin and External Beam Radiation Followed by Gemcitabine and Bevacizumab for Locally Advanced Pancreatic Cancer

Status:
Terminated

Trial end date:
2009-07-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is determine the safety of bevacizumab, oxaliplatin, 5-FU, and gemcitabine in combination with external beam radiation therapy(Phase I portion) as well as to begin to collect information about whether this combination treatment is effective in treating patients with locally advanced pancreatic cancer (Phase II portion).

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

Massachusetts General Hospital

Collaborators:

Beth Israel Deaconess Medical Center
Dana-Farber Cancer Institute
Genentech, Inc.
Sanofi

Treatments:

Angiogenesis Inhibitors
Bevacizumab
Fluorouracil
Gemcitabine
Oxaliplatin