Study of Blood Clotting After Transcatheter Atrial Septal Defect Closure

• Status: Unknown status
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate blood clots after Percutaneous ASD Closure in different age, sexuality and defective diameter; evaluating the relationship of blood clotting with Occluder, injury of intima and inflammation;comparation of the effect and safety between different anticoagulation after Percutaneous ASD Repair; explore propose an optimal anticoagulation plan.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Third Military Medical University
• Collaborator: Chongqing Medical University
• Treatments: Calcium heparin; Dalteparin; Enoxaparin; Heparin; Heparin, Low-Molecular-Weight; Tinzaparin

Criteria

Inclusion Criteria:

• Age≥3 years

• Diameter of defect≥5mm and increasing volume load of right heart

• ≤36 mm secondary left to right shunt

• The distance between defective edge and coronaria venosus sinus, inferior caval vein, superior vena and pulmonary vein≥ 5 mm, between artrial-ventricular valve≥7 mm

• The diameter of defect>Occluder

• No other cardiac anomalies need surgery intervention

Exclusion Criteria:

• Hypertension

• Coronary artery disease

• Diabetes

• Atrial fibrillation and oral contraceptive medication

• Aspro, clopidogrel and warfarin in 2 weeks.