Overview

Study of Calcium Plus Vitamin D Supplementation in Prevention of Colorectal Adenomas Recurrence

Status:
Unknown status
Trial end date:
2019-02-01
Target enrollment:
0
Participant gender:
All
Summary
Calcium plus vitamin D may be effective in the prevention of colorectal adenoma recurrence. The aim of this study is to investigate the effect of supplementation with calcium plus vitamin D on the recurrence of colorectal adenomas.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Collaborator:
Ministry of Science and Technology of the People´s Republic of China
Treatments:
Calcium, Dietary
Ergocalciferols
Vitamin D
Vitamins
Criteria
Inclusion Criteria:

- Individuals aged 18-65years

- Individuals who had at least one histologically confirmed colorectal adenoma removed
within three months before recruitment

- Individuals without a history of familial polyposis

- Those who voluntarily sign the consent form after being fully informed and
understanding the purpose and procedures of the study , characters of the disease,
effect of medications, methods of related examinations, and potential risk/benefits of
the study

Exclusion Criteria:

- Patients who are hypersensitive or intolerant to the drugs

- Patients who are intolerant to another colonoscopy examination

- Patients with hypercalcemia or urolithiasis

- Pregnant women, women during breast-feeding period, or women with expect pregnancy

- Patients with diabetes mellitus, severe heart or renal disease, or cancer history

- Patients with a history of subtotal gastrectomy or partial bowel resection

- Patients who are not able to cooperate

- Individual who are involved in designing, planning or performing this clinical trial

- Patients with medical conditions who are not appropriate to participate the study

- Patients who are taking aspirin, NSAIDs or COX2 inhibitors

- Patients who are taking folic acid or Butyrate.

- Patients with IBD