Study of Chemoradiotherapy Combined With Cetuximab in Nasopharyngeal Carcinoma
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
This is an open, multicenter phase Ⅱ clinical trial. The purpose of this study is to evaluate
acute toxicity and efficacy of cetuximab (C225) combined with IMRT + neoadjuvant chemotherapy
in advanced T stage of nasopharyngeal carcinoma. Besides, to figure out the relationship
between patient outcome and EGFR gene copy number, expression and mutation.
Phase:
Phase 2
Details
Lead Sponsor:
Sun Yat-sen University
Collaborators:
Affiliated Cancer Hospital of Shantou University Medical College Cancer Hospital of Shantou University First People's Hospital of Foshan Hubei Cancer Hospital Hunan Cancer Hospital Jiangxi Provincial Cancer Hospital Shenzhen People's Hospital The First Affiliate Hospital of Guangxi Medical College Tongji University Wenzhou Medical University Wuhan Union Hospital, China Wuhan University Xijing Hospital Zhejiang Cancer Hospital