Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode)

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether colchicine is safe and effective in the treatment and prevention of recurrent pericarditis (first episode).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Azienda Sanitaria Locale 3, Torino
• Treatments: Colchicine

Criteria

Inclusion Criteria:

• Patients with the first attack of recurrent pericarditis

• Age≥ 18 years

• Informed consent

Exclusion Criteria:

• Suspected neoplastic, tuberculous, or purulent etiology

• Known severe liver disease and/or elevated transaminases >1.5 times the upper limit of normality

• Serum creatinine >2.5 mg/dl

• Serum creatine kinase (CK) over the upper limit of normality or known myopathy

• Known gastrointestinal or blood disease

• Pregnant or lactating women or women not protected by a contraception method

• Known hypersensibility to colchicine

• Treatment with colchicine at enrolment