Study of Count Coughs in Subjects With Acute Upper Respiratory Tract Infections
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
The objectives of this study are: a) to assess the feasibility and sensitivity of manually
count cough bouts over a 4-hour period; b) to assess the effects of buckwheat honey and
guaifenesin 400 mg immediate release tablets compared to placebo on the frequency and
severity of acute cough due to upper respiratory tract infection and c) to evaluate the
correlation between cough bout frequency and subjective assessments of cough severity. The
hypotheses to be tested is that 10 ml of buckwheat honey and 400 mg of immediate release
guaifenesin will significantly reduce the frequency and severity of cough compared to placebo
over a 4-hour evaluation period.
Phase:
N/A
Details
Lead Sponsor:
Wyeth is now a wholly owned subsidiary of Pfizer
Treatments:
Chlorpheniramine, phenylpropanolamine drug combination Guaifenesin Phenylpropanolamine