Study of Early Nutritional Intervention During Concurrent Chemoradiotherapy for Local Advanced Non-small Cell Lung Cancer

• Status: Completed
• Trial end date: 2023-08-31
• Target enrollment: 0
• Participant gender: All

Summary

This single-arm phase II prospective study is to determine the efficacy of early nutritional intervention during concurrent chemoradiotherapy for local advanced non-small cell lung cancer.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-sen University

Criteria

Inclusion Criteria:

• Confirmed unresectable stage IIIA-IIIC non-small cell lung cancer.

• Recieved definitive concurrent chemoradiotherapy.

• Pretreatment PG-SGA score A or B.

• Eastern Cooperative Oncology Group (ECOG) performance status 0-1.

• Estimated life expectancy of at least 6 months.

• Without contraindication for chemoradiotherapy.

Exclusion Criteria:

• Severe impairment of intestinal function, or intolerance of enteral nutrition.

• Severe vomiting, gastrointestinal bleeding, or intestinal obstruction.

• Severe malnutrition, or intolerance of chemoradiotherapy.