Study of Growing Biofilm by an Antiplaque Mouthrinse

• Status: Completed
• Trial end date: 2009-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the efficiency of a new mouthrinse on dental plaque deposits.

The study is carried out on 50 volunteers that are asked to use the mouthrinse without any other oral hygiene measure, during 4 days. It is a double bind, cross-over, randomized design: the same subjects test the active product and the placebo.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Bordeaux
• Treatments: Grape Seed Extract

Criteria

Inclusion Criteria:

• Healthy volunteer

• without caries

• with at least 20 natural teeth excluding third molars

• Women using contraceptives for at least twelve weeks and while on study

• Protected by French social security system

• Written informed consent

Exclusion Criteria:

• Pregnancy or breast feeding

• Volunteers with partial denture or orthodontic appliance

• Person protected by the law who

• Person unable to give their consent to participate to the study.

• Under aged

• Current participation in another clinical trial

• Oral pathologies

• Systemic diseases

• Volunteers allergic to of the componentst of the tested products

• Volunteers with hyposalivation or xerostomia

• Treatment with antibiotics o intestinal antiseptics within 3 month before inclusion

• Treatment with oral antiseptics within 1 month before inclusion

• Alcoholic consumption more than 20 g/day (or 2 glasses)

• Heavy smokers

• Volunteers drinking a lot of tea or coffee