Overview

Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure

Status:
Completed
Trial end date:
2016-06-06
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to test the hypothesis that high-dose spironolactone will lead to greater proportional reduction in NT-proBNP levels from randomization to 96 hours over standard of care.
Phase:
Phase 2
Details
Lead Sponsor:
Duke University
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Spironolactone